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            熱門關鍵詞:tct耗材液基細胞處理試劑盒代理病理組織標本固定劑環保組織固定液

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            液基細胞學技術與傳統細胞學涂片檢測宮頸鱗狀細胞病變的比較

            文章出處:責任編輯:作者:人氣:-發表時間:2018-02-23 09:09:00【

             摘要

            目的:評價液基細胞學技術與傳統細胞學涂片檢測宮頸鱗狀細胞病變 的差異.方法:比較同地區、同期宮頸液基細胞學篩查病例及傳統細胞學涂片篩查病例,同時收集液基細胞組中289例陰道鏡檢查及病理活檢結果及傳統細胞組中 62例陰道鏡檢查及病理活檢結果進行分析,評估不同病變的假陽性率.結果:液基細胞組標本不滿意率(2.71)明顯低于傳統細胞組標本(3.96) (P0.01).液基細胞組對不明意義的非典型鱗狀細胞(ASC - US)及更高級別的病變檢出率(2.25)明顯高于傳統細胞組(0.74)(P0.01).液基細胞組ASC - US占低度鱗狀上皮內病變(LSIL)、非典型鱗狀細胞不除外高度病變( ASC - H)、高度鱗狀上皮內病變(HSIL)及鱗癌(SCC)總數的比例(0.82)明顯低于傳統細胞組(2.11)(P0.01).傳統細胞組與液基細 胞組假陽性率比較,差異有統計學意義(P0.01),傳統細胞組ASC -USASC -HSCC中假陽性率與液基細胞組比較差異無統計學意義.組織學活檢與細胞學結果比較,年齡≥35液基細胞ASC - US陽性預測值與傳統細胞組比較差異無統計學意義(P0.01);年齡<35液基細胞組ASC - US陽性預測值明顯高于傳統細胞組(P0.01).結論:液基細胞學技術檢測宮頸鱗狀細胞病變明顯優于傳統細胞學涂片,高質量的宮頸細胞標本對提高診斷 的準確性非常重要;選擇不同方法篩查宮頸病變時,目標人群的年齡是一個重要的決定因素(中山市康乃欣生物醫療科技有限公司摘錄www.tjxinqixiong.com

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